Multichannel-systems USB-MEA256-System Manual Manuel d'utilisateur

USB-MEA256-System Manual

USB-MEA256-System Manual 4 2.3 Important Safety Advice Warning: Make sure to read the following advice prior to installation or use of the device an

5 3 Software Installation 3.1 Software Installation Please check the system requirements before you install the MC_Rack software. MCS cannot guarante

USB-MEA256-System Manual 6 3.1.2 Recommended BIOS settings Recommended operating system settings The following automatic services of the Windows opera

Software Installation 7 3.1.4 First Use of MC_Rack It is also not recommended to run any applications in the background when using MC_Rack. Remove al

9 4 USB-MEA256-System 4.1 The USB-MEA256 Data Acquisition Analog input signals are acquired from the data source and digitized by the 256-channel an

USB-MEA256-System Manual 10 If necessary, you can use a Faraday cage or appropriate materials, for example, aluminum foil, for shielding the amplifie

USB-MEA256-System 11 4.4 256 Thin MEA The glass part of 256 Thin MEAs are only 180 μm "thick", ideally suited for high-resolution imaging.

USB-MEA256-System Manual 12 4.6 The USB-MEA256-System USB-MEA256-System is a high flexible system with integrated amplification, data acquisition, and

USB-MEA256-System 13 4.8 Setting Up the Amplifier Open the lid of the amplifier. Place the 256MEA test model probe inside. Replace the lid and close

USB-MEA256-System Manual 14 General Performance / Noise Level Please use the provided test model probe to test the amplifier immediately after install

USB-MEA256-System 15 The following screen shot shows a recording from a USB-MEA256-System with a test model probe and a sampling rate of 40 kHz. Set

USB-MEA256-System Manual 16 Replace the lid and close it carefully. Warning: Spilled liquid can damage or even completely destroy the electronics o

USB-MEA256-System 17 Using 256MEA Electrodes for Stimulation The electrodes of the 256MEAs can also be used for electrical stimulation. Around the ope

USB-MEA256-System Manual 18 Using 256-9wellMEA Electrodes for Stimulation Each well of the nine wells of the 256-9wellMEA is equipped with 26 round re

USB-MEA256-System 19 4.9 The USB-MEA256 Device 4.9.1 Rear Panel DIGITAL IN / OUT A Digital IN / OUT for 16 digital in- and output bits is available (

USB-MEA256-System Manual 20 Audio Output AUDIO To the AUDIO OUT (3.5 mm phone jack) you can connect an audio system to make the electrical activity au

USB-MEA256-System 21 Cabling For D0 IN and D0 OUT, and Analog Input A1 to A4 on the rear panel of the device you need coaxial cable: Lemo cable with o

23 5 Troubleshooting 5.1 Troubleshooting The following hints are provided to solve special problems that have been reported by users. Most problems

Information in this document is subject to change without notice. No part of this document may be reproduced or transmitted without the express w

USB-MEA256-System Manual 24 5.3 Triggering / Digital Input does not Work You have connected a TTL source (for example, the Sync Out of a stimulus gen

Troubleshooting 25 5.5 MEA is defective MEAs wear out after multiple uses or over a longer time of use, for example, for long-term cultures. This is c

USB-MEA256-System Manual 26 5.7 Missing Spikes or Strange Signal Behavior MEAs wear out after multiple uses or over a longer time of use, for example

27 6 Appendix 6.1 Technical Support Please read the chapter "Troubleshooting" of the user manual first. Most problems are caused by minor

USB-MEA256-System Manual 28 6.2 Technical Specifications The USB-MEA256-System is a 252 + 4 channels amplifier with integrated analog / digital board

Appendix 29 Data converter and USB interface: Sampling frequency up to 40 kHz Maximal data rate 20.5 MB/s Data resolution 16 Bit USB Version

USB-MEA256-System Manual 30 6.3 Pin Layout Analog IN A1 to A4 Please note that the channels 127, 128, 255 and 256 are not used for recording analog r

Appendix 31 USB-MEA256-System Amplifier: Stimulation Connector Sockets 1 to 4 USB-MEA256-System Amplifier: Spring Contacts Number o

USB-MEA256-System Manual 32 6.4 Test Model Probe The provided model test probe simulates a 256MEA with a resistor of 220 k and a 1 nF capacitor betw

Appendix 33 6.5 Data Sheet 256MEA

Multi Channel SystemsMCS GmbHAspenhaustrasse 2172770 ReutlingenGermanyFon +49-7121-9 09 25- 0Fax +49-7121-9 09 [email protected]

B 2 C 3 C 1 G 7 D 2 G 6 E 3 E 1 F 4 F 2 G 5 G 3 G 1 H 4 H 2 H 6 I 7 I 1 I 3 I 5 K 2 K 4 L 1 L 3 L 5 M 2 M 4 N

Multi Channel SystemsMCS GmbHAspenhaustrasse 2172770 ReutlingenGermanyFon +49-7121-9 09 25- 0Fax +49-7121-9 09 [email protected]

USB-MEA256-System Manual 34 6.6 Data Sheet 256ThinMEA

Multi Channel SystemsMCS GmbHAspenhaustrasse 2172770 ReutlingenGermanyFon +49-7121-9 09 25- 0Fax +49-7121-9 09 [email protected]

Multi Channel SystemsMCS GmbHAspenhaustrasse 2172770 ReutlingenGermanyFon +49-7121-9 09 25- 0Fax +49-7121-9 09 [email protected]

Stimulation Connector Socket 3 Electrode ID Stim. Socket Spring Contact Hardware ID C15 61 98 239 C16 62 222 209 D13 63 99 171 D14 57 96 184 D15 58 2

Appendix 35 6.7 Data Sheet 256-9wellMEA

256-9wellMEA256-9wellMEA300/30iR-ITO-w/o256-9wellMEA300/30iR-ITO-mqMulti Channel SystemsMCS GmbHAspenhaustrasse 2172770 ReutlingenGermanyFon +49-7121-

Multi Channel SystemsMCS GmbHAspenhaustrasse 2172770 ReutlingenGermanyFon +49-7121-9 09 25- 0Fax +49-7121-9 09 [email protected]

iii Table of Contents 1 Introduction 1 1.1 About this Manual 1 1.2 Welcome to the USB-MEA256-System 2 2 Important Safety Advice 3 2.1 Oper

256-9wellMEAA12 A22 A32 A42 A52 A62Multi Channel SystemsMCS GmbHAspenhaustrasse 2172770 ReutlingenGermanyFon +49-7121-9 09 25- 0Fax +

Multi Channel SystemsMCS GmbHAspenhaustrasse 2172770 ReutlingenGermanyFon +49-7121-9 09 25- 0Fax +49-7121-9 09 [email protected]

Multi Channel SystemsMCS GmbHAspenhaustrasse 2172770 ReutlingenGermanyFon +49-7121-9 09 25- 0Fax +49-7121-9 09 25-11info@multichanne

USB-MEA256-System Manual 36 6.8 Data Sheet 256MEA-STIM-C-Con

Multi Channel SystemsMCS GmbHAspenhaustrasse 2172770 ReutlingenGermanyFon +49-7121-9 09 25- 0Fax +49-7121-9 09 [email protected]

Appendix 37 6.9 Data Sheet 256MEA-9well-STIM-ADPT

Multi Channel SystemsMCS GmbHAspenhaustrasse 2172770 ReutlingenGermanyFon +49-7121-9 09 25- 0Fax +49-7121-9 09 [email protected]

USB-MEA256-System Manual 38 6.10 256MEA-Signal Generator

Multi Channel SystemsMCS GmbHAspenhaustrasse 2172770 ReutlingenGermanyFon +49-7121-9 09 25- 0Fax +49-7121-9 09 [email protected]

Multi Channel SystemsMCS GmbHAspenhaustrasse 2172770 ReutlingenGermanyFon +49-7121-9 09 25- 0Fax +49-7121-9 09 [email protected]

USB-MEA256-System Manual iv 6 Appendix 27 6.1 Technical Support 27 6.2 Technical Specifications 28 6.3 Pin Layout 30 6.4 Test Model Probe

Appendix 39 6.11 Digital IN / OUT Extension 16 bit Digital IN / OUT Connector (68-Pin MCS Standard Connector) Pin 1 GNDP (power ground) Pin 2

USB-MEA256-System Manual 40 6.12 Scope of Delivery 1 USB-MEA256-System 1 Data acquisition computer 1 USB 2.0 high speed cable (type A - mini B) 4

41 7 Index

USB-MEA256-System Manual 42

43 1 16-bit digital IN / OUT 1, 9 2 256MEA 9, 10, 23, 30 16x16 grid...10 Electrode diameter ...

USB-MEA256-System Manual 44 U USB 1, 11, 27 USB hub 11 USB-MEA256-System 1, 11 Using Electrodes for Stimulation 12 Pin Layout ...

45

1 1 Introduction 1.1 About this Manual It is assumed that you already have a basic understanding of technical and software terms. No special skills

USB-MEA256-System Manual 2 1.2 Welcome to the USB-MEA256-System The USB-MEA256-System is a compact and portable stand-alone solution for MEA recordi

3 2 Important Safety Advice 2.1 Operator's Obligations The operator is obliged to allow only persons to work on the device, who  are familiar